This article contains information about the literary events and publications of 1522.
- September 21 – Luther Bible: Martin Luther's translation of the Bible's New Testament into Early New High German from Greek, Das newe Testament Deutzsch, is published in Germany, selling thousands in the first few weeks.
- Luo Guanzhong's 14th-century compilation Romance of the Three Kingdoms is first printed, as Sanguozhi Tongsu Yanyi.
- Desiderius Erasmus – Novum Testamentum (Greek Textus Receptus of the New Testament, third edition)
- Martin Luther – Against Henry, King of the English (Contra Henricum Regem Anglie)
- Adam Ries – Rechenung auff der Linihen und Federn
- Niklaus Manuel Deutsch I – Vom Papst und Christi Gegensatz
- The World and the Child (Mundus et Infans, published)
- February – Jean de Nostredame, Provençal historian (died c.1576)
- June 1 – Dirck Volckertszoon Coornhert, Dutch classical scholar (died 1590)
- unknown dates
- January 25 – Raffaello Maffei, Italian humanist historian and theologian (born 1451)
- February 25 – William Lilye, English classical scholar (born c. 1468)
- June 30 – Johann Reuchlin, German humanist scholar and poet (born 1455)
- September – Gavin Douglas, Scottish poet and bishop (born c. 1474)
- Thomas, Calvin (1909). A History of German Literature. New York: D. Appleton & Co. Retrieved 2009-12-14.
- Harry G. Lang; Harry G Lang; Bonnie Meath-Lang (1995). Deaf Persons in the Arts and Sciences: A Biographical Dictionary. Greenwood Publishing Group. p. 98. ISBN 978-0-313-29170-8.
- Peter G. Bietenholz; Thomas Brian Deutscher (1 January 2003). Contemporaries of Erasmus: A Biographical Register of the Renaissance and Reformation. University of Toronto Press. p. 366. ISBN 978-0-8020-8577-1.
- Arthur F. Kinney; David W. Swain; Eugene D. Hill; William A. Long (17 November 2000). Tudor England: An Encyclopedia. Routledge. p. 200. ISBN 978-1-136-74530-0.